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27 April
Afghanistan and Pakistan vaccinate over 40 million children against polio

Two of the four remaining countries which have never stopped polio vaccinated over 40 million children between them this week.
The two countries share a long border with regular
travel and are considered a single block of transmission for the poliovirus. Impressions of the campaign can be downloaded from the WHO weekly podcast episode of 27 April (polio story starts at 4:40 minutes).  

Since the introduction of new tool – including more potent vaccines – and new tactics in both countries in 2006, both appear to have stopped the bulk of their indigenous polio. Authorities are now focusing on the inter-country reservoirs, where access is complicated by security and population mobility, among other factors. Stopping polio in these reservoirs requires careful international coordination and real synchronization of activities at borders, as well as concrete help to improve safety, even temporarily. In both countries, vaccinators aim to reach all children under the age of five: in Afghanistan, this means 7.3 million children; in Pakistan, 33.5 million.

Only two other countries have never stopped polio – India and Nigeria, both with larger populations and much more intense transmission of virus than Afghanistan and Pakistan. In 2006, Afghanistan and Pakistan reported 31 and 40 cases of polio respectively; India and Nigeria had 674 and 1127 respectively. The independent advisory group to the global eradication effort concluded last year that 2007 presents the best chance for Afghanistan and Pakistan to be the next countries to stop poliovirus. Afghanistan has had no cases of polio since November 2006.

The global drive to eradicate polio, which has reduced the number of polio cases worldwide by over 99%, is predicated on reaching all children under five years of age with oral polio vaccine multiple times.
 

 

 

 

 

 

 

 

 

 

 

 

 


21 April
Studies confirm cost-effectiveness of polio eradication and greater efficacy of new oral polio vaccine

Leading medical journal The Lancet published today two studies with important implications for the Polio Eradication Initiative. Read their press release (in PDF format)

Monovalent vaccine three times as effective as trivalent

A new study by Imperial College shows that monovalent oral polio vaccine type 1 (mOPV1) is three times more effective than trivalent OPV at protecting children against type 1 polio in Uttar Pradesh, India.  The study highlights that wide-scale use of mOPV1 substantially raises the population immunity levels compared to the same number of doses of trivalent OPV, improving the prospects of more rapidly interrupting the remaining chains of endemic polio transmission. 

India's success in stopping polio now depends on further improving large-scale campaigns in order to reach every child with mOPV1.

For more details, see:

Eradicating polio cheaper in the long run

In the same issue of The Lancet, a new study by Kim Thompson et al from Harvard University demonstrates that effective control of polio (i.e., maintaining low numbers of polio cases) would cost more in the long-term – both in human suffering and dollars – than finishing eradication. 

The study also suggests that eradication is more cost-effective than other, lower-control options (resulting in higher numbers of cases); additional research is under way to model more fully these other options, including a reduction or halt to supplementary immunization activities and the attendant human and financial costs.

For further information, please visit:


10 April
Indian high-speed train delivers polio vaccine

On April 8, children in 17 districts of Bihar lined up for their two drops of oral polio vaccine.
On April 5, that vaccine had been unloaded from the Rajdhani Express, one of India's fastest trains, having travelled through several states to get there on time. The express delivery was just one part of India's intense efforts to stop polio in its two northern endemic states.

During the planning stages leading up to the vaccination campaign, medical officers in the state capital Patna alerted their colleagues in other states that they were short of vaccine. Phone calls and emails flew between staff of the National Polio Surveillance Project (NPSP) and Rotary, partners in India's polio eradication efforts, to find and deliver vaccine from other parts of the country. With the go-ahead from and oversight of Dr. P. Biswal from the Government of India, the plan swung into action.

 

 

Rotary arranged for special permission from the Union Railway Minister Laloo Prasad Yadav to transport 3.3 million doses from Delhi, Haryana, Punjab and Uttar Pradesh on the high-speed Rajdhani Express. To ensure that the vaccine arrived on time and at the necessary chilled temperatures, NPSP staff monitored its packing and safe transportation along the way.

At the same time, a Rotary-hired truck took 700,000 doses of vaccine from Lucknow, in the neighbouring state of Uttar Pradesh, to Patna. The truck was escorted and tracked by NPSP staff every step of the way, with surveillance medical officers, drivers, and even janitors from the NPSP district offices all pitching in to make sure the vaccine moved smoothly between district and state borders. On Polio Sunday, as the immunization days are known in India, children in Bihar had their polio doses ready for them.

 

 


3 April 
Polio Eradication Initiative mourns the death of advisor Aileen Plant

It is with great sadness that the Global Polio Eradication Initiative bids farewell to one of its own, Dr Aileen Plant. Dr Plant passed away suddenly on 27 March, at Jakarta airport, on her way home from a World Health Organization meeting.

Dr. Aileen Plant is mourned by the polio eradication community, personally and professionally.

An Australian, Dr Plant was a world-renowned epidemiologist and public health leader. A respected lecturer, teacher and writer, she was considered a mentor by many in the international public health community. 

In addition to her many roles in the global public health arena, Dr Plant was a member of the Advisory Committee on Polio Eradication (ACPE). The technical oversight body of the Global Polio Eradication Initiative, the ACPE benefited immensely from Dr. Plant's objective, straightforward and frank advice on polio eradication. 

Aileen Plant exemplified the best in public health service through her sense of duty, ethics, courage and professionalism. "It is with profound sadness that we learnt of the sudden passing of our dear colleague Dr Aileen Plant," said Professor Barry Schoub, fellow ACPE member from Johannesburg. "She was a very warm, friendly, compassionate, dedicated and insightful person, and she will be sorely missed. Our thoughts go out to her family and friends who we hope will draw some comfort from the esteem and high regard which her colleagues held for her."

 

The Global Eradication of Polio