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May
2007 Data as of 15 May
2007
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Headlines
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WHA urges
intensification of polio efforts:
At the World Health Assembly (WHA) in Geneva, Member
States adopted a resolution urging an intensification of eradication efforts
to rapidly interrupt the remaining chains of indigenous transmission and
further limit potential international spread of the virus.
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'Case for polio eradication' presented at WHA:
In follow-up to the WHO Director-General (DG)
Dr Margaret Chan's 28 February Urgent Stakeholder Consultation, a side
meeting with key stakeholders was held in the margins of the WHA, to discuss
the DG's final 'Case for Completing Polio Eradication'. The 'Case' document
summarizes the financial and humanitarian benefits of completing polio
eradication, and is setting the stage for intensive resource mobilization
activities to fill the 2007-2008 global funding gap of US$ 540 million.
"Finishing the job of polio eradication is our best buy," said Dr Chan in
her opening remarks to the WHA. "We must do it. We are leaving a perpetual
gift to generations of children to come." The 'Case' document is available
at
http://www.polioeradication.org/content/general/TheCase_FINAL.pdf .
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Immediate injection of cash urgently needed:
By July 2007, the Global Polio
Eradication Initiative will have a negative cash flow, which if not
addressed will require an immediate reduction in planned polio eradication
activities in the remaining infected countries. Even a temporary cutback
would result in the reinfection of polio-free areas, delays in outbreak
response, a surge in polio-paralyzed children and an increase in overall
costs. Insufficient funds at this late stage imperil the entire 20-year
eradication effort, as well as related gains in routine childhood
immunization, global communicable disease control, preparedness and
response, and other child survival and international health activities. For
further information, please visit
www.polioeradication.org/fundingbackground.asp .
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WHO DG meets Afghanistan and Pakistan heads of state on polio :
On 29 April and 1 May, WHO
Director-General Dr Margaret Chan and EMRO Regional Director Dr Hussein A
Gezairy met with President Hamid Karzai of Afghanistan, and Prime Minister
Shaukat Aziz of Pakistan. Discussions focused on both countries' combined
efforts to interrupt the final chains of polio transmission which straddle
their common border. In particular, the leaders discussed new approaches to
increasing access to all populations, including the use of Days of
Tranquility in Afghanistan, engaging semi-autonomous populations in Pakistan
and reaching mobile populations travelling across the common border. In
Afghanistan, Dr Chan also met with NATO and the International Security
Assistance Force to explore ways of negotiating pauses in conflict to allow
polio vaccination teams safe passage during campaigns. For further
information, please click
here.
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Lancet studies show cost-effectiveness of polio eradication and efficacy of
monovalent OPV type 1: The
Lancet published two studies with important implications for the Global
Polio Eradication Initiative. The first study, by Kim Thompson et al from
Harvard University, demonstrates the cost-effectiveness of polio
eradication, both from an economic and public health point of view. The
second study, by Nick Grassly et al from the Imperial College of London,
highlights the greater efficacy of the new monovalent oral polio vaccine
type 1 (mOPV1) compared with trivalent OPV. For
detailed interpretations of both studies,
please click
here.
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Polio confirmed in Myanmar:
a polio case is confirmed in Myanmar, the first wild polio in the country
since 2000 and is most likely an importation. (See 'Re-infected countries'
section below, for further details.)
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Less type 1 than type 3 polio in 2007:
In 2007, for the first time ever, there are fewer type 1 polio cases than
type 3 cases in the endemic areas (see 'Nigeria', 'India' and 'Pakistan'
sections below). This suggests that the strategy of large-scale use of
monovalent oral polio vaccine type 1 (mOPV1) to prioritize the eradication
of this virus, given its historically higher disease burden and potential to
spread internationally, is working.
Country Focus
Nigeria
- In 2007, 73 cases have been reported, of
which 56 are due to type 3 poliovirus.
- The government's National Programme for
Immunization (NPI) has now been integrated with the National Primary Health
Care Development Agency. All efforts must be undertaken to ensure that this
move does not adversely affect the gains made in polio eradication and
routine immunization over the past 12 months.
- The Expert Review Committee on Polio
Eradication (ERC) convened in Abuja on 3-4 May. The ERC noted the steep
decline (78%) in type 1 polio in 2007 compared to previous year, as well as
progress achieved towards strengthening of routine immunization and polio
eradication. At the same time, however, the ERC highlighted the need to
close the immunity gap in critical northern states (some of which still have
25% of children below five years of age who have never received a dose of
OPV), through higher quality immunization campaigns achieving consistently
high coverage.
- The next Immunization Plus Days (IPDs)
will be held on 23-26 June.
India
- In 2007, 48 cases
have been reported. In Uttar Pradesh state, one of only two remaining
endemic states (along with Bihar), 18 of the state's 28 cases are due to
type 3 poliovirus. No type 1 polio has been reported in the five
traditional high-risk districts of western Uttar Pradesh (Moradabad, JP
Nagar, Bareilly, Rampur, Badaun), since 2 October 2006.
- Four large-scale immunization campaigns
have already been conducted in 2007 with mOPV1. To support campaigns in key
high risk districts, WHO surveillance medical officers (SMOs) from
polio-free areas are routinely re-deployed.
- A recent campaign on 8 April was made
possible in part thanks to a rapid, last-minute effort by polio partners
Rotary and the National Polio Surveillance Project (NPSP). During the
planning stages of the campaign, it became apparent that a vaccine-shortfall
of more than four million doses was going to affect 17 districts in Bihar.
To ensure this shortfall was filled in time of the campaign, Rotary arranged
for special permission from Union Railway Minister Laloo Prasad Yadav, to
transport 3.3 million doses of vaccine from Delhi, Haryana, Punjab and Uttar
Pradesh, on the high-speed Rajdhani Express train. At the same time, a
Rotary-hired truck took 700,000 doses of vaccine from Lucknow, Uttar
Pradesh, to Patna, Bihar.
- New Chief Minister of Uttar Pradesh,
Mayawati, called polio eradication a state priority, as she launched the
most recent campaigns.
Afghanistan
and Pakistan
- In 2007, in Pakistan, 7
cases have been reported; 2 cases has been reported in Afghanistan. In
Pakistan, 5 of the 7 cases are due to type 3 polio.
- A joint
Afghanistan/Pakistan Technical Advisory Group (TAG) convened in Islamabad on
17-19 April, to review epidemiological and programmatic data. The TAG
highlighted that real progress was achieved in 2006, with the virus now
limited to known reservoirs that straddle the two countries and which must
be tackled together. The TAG's recommendations focused on intensifying
efforts in areas of known polio transmission, and increasing access to
populations living in insecure areas, semi-autonomous populations and mobile
populations.
- In April, Pakistan and
Afghanistan coordinated the fourth large-scale immunization campaign of 2007
(following activities in January, February and March), collectively reaching
nearly 50 million children under the age of five years. Focus was again on
increasing access to populations in border areas and mobile populations.
Nomadic routes were mapped, and vaccination points were set up at key
gathering places and at major border-crossings.
- Officially launching
polio immunization activities in Pakistan, Prime Minister Shaukat Aziz
re-affirmed the government's commitment, vowing: "Pakistan is committed to
eradicate polio from the country very soon."
- An audio-slideshow of
polio vaccination campaigns along the Afghanistan-Pakistan border is
available for viewing (and in downloadable format) at
www.polioeradication.org .
Re-infected countries
- Myanmar is
currently planning a targeted polio immunization campaign as a rapid
response to a probable importation from neighbouring Bangladesh, and in
advance of the onset of the rainy season in July. Three large-scale,
internationally-coordinated cross-border campaigns with Bangladesh are being
planned, the first of which was held in mid-May. Active disease
surveillance activities are also ongoing in the area, to rapidly detect any
further cases.
- In the Democratic
Republic of the Congo (DR Congo), 2 of the 3 outbreaks due to imported
poliovirus from Angola appear to have been stopped, with expanded
outbreak response activities continuing to address the ongoing transmission
in Bandundu/Equateur provinces. A total of 12 cases have been reported in
DR Congo this year. Although no new cases have been reported from Angola
this year, undetected circulation cannot be ruled out due to ongoing
subnational surveillance gaps (as confirmed by genetic sequencing of the
2006 cases in Angola and some of the 2007 cases from DR Congo). At an
Angola TAG meeting held in April, rapidly filling these surveillance gaps
was discussed.
- In the Horn of Africa,
outbreak response activities are continuing to stop the two known areas of
ongoing transmission, in the cross-border area in northern Somalia and the
Somali region of Ethiopia, and central Somalia. At a Horn of Africa TAG
meeting in April, the need for intensified cross-border activities was
highlighted.
- Niger and
Nepal continue to be at particular risk of repeated, isolated polio
importations, due to their geographic proximity to endemic areas (northern
Nigeria, and Bihar and Uttar Pradesh, India).
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The state of polio eradication |
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The world now has a second and best chance to eradicate polio:
almost all outbreaks in re-infected countries after the
international spread of 2003-2006 have been stopped. Only four
parts of four countries have never interrupted indigenous wild
poliovirus transmission: Nigeria, India, Pakistan and Afghanistan.
Global polio eradication depends on the
engagement of the leaders of these four countries.
The tools to eradicate polio are better than ever. The programme now has vaccines which
are twice as effective and diagnostic tools that detect and track
poliovirus twice as fast.
Policies to minimize the risks and consequences of international
spread of poliovirus are now in place:
travellers to and from polio-endemic countries are advised to be
fully vaccinated before travel. |
The remaining challenges to a polio-free world are:
1. Rapidly overcoming the remaining operational challenges to
reaching every child in the four endemic areas of Nigeria, India,
Pakistan and Afghanistan.
2. Rapidly making available the necessary financial resources to
fully implement polio eradication strategies.
3. Continue outbreak response activities in the remaining
re-infected countries, and minimise the risk and consequences of
further international spread of polio.
4. Increasing polio vaccination coverage through routine
immunization services.
5. Maintaining high quality AFP surveillance in all countries. |
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Polio eradication will only succeed if the necessary funds are made
available, and with strong political commitment in polio-affected countries.
More than 10 million children will be paralysed in the next 40 years if the
world fails to capitalize on its >US$5 billion global investment in eradication.
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