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November 2009
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All data as of 03 December 2009
The December-January report will be produced at the end of January
Afghanistan to be first country to use bivalent oral polio vaccine
(bOPV) in Supplementary Immunization Activities for polio eradication:
The 13-15 December vaccination campaigns in the country will be conducted using
this new formulation of polio vaccine, which protects children from both
surviving strains of wild poliovirus concurrently and greatly simplifies
logistics.
Advisory Committee on Poliomyelitis Eradication (ACPE) holds special
consultation: The ACPE was joined by spearheading partners of the Global
Polio Eradication Initiative (GPEI), governments of endemic and polio-affected
countries, and donors, in Geneva on 18-19 November. The ACPE evaluated the
impact of the 2009 Programme of Work, including the
Independent Evaluation of Major Barriers to Interrupting Poliovirus
Transmission, reviewed the outcomes of the clinical trials on the new bivalent
oral polio vaccine (bOPV) and looked closely at the epidemiological trends in
the remaining four endemic countries, as well as the measures put in place to
limit international spread of wild poliovirus. These discussions mark the start
of a wide-ranging consultative process for the development of a new Programme of
Work, with finalization as soon as possible after the January 2010 meeting of
the WHO Executive Board. The full recommendations of the ACPE are available at
the Weekly
Epidemiological Record.
The ACPE
recommendations for the endemic countries included:
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Maintain Head of State engagement and oversight to ensure accountability of
local authorities in ensuring that all children are reached by immunization
activities;
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Optimize use of available vaccine tools, by rapidly introducing bOPV;
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Conduct independent management reviews of key areas where management,
operational constraints and lack of accountability continue to affect
Supplementary Immunization Activity (SIA) quality, in order to identify root
causes of programme problems and identify solutions;
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Develop district-specific plans for security-compromised areas to ensure
tailored strategies to access children, including through negotiated access
with parties to the conflict;
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Adopt sero-surveillance as an additional monitoring tool, particularly in
areas of discordant programmatic and epidemiological data, to verify
programme performance and vaccine efficacy and to guide strategy;
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Expand environmental surveillance appropriately to provide information that
will be supplemental to AFP surveillance in assessing the persistence of
wild poliovirus;
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Continue to systematically re-assess community knowledge, attitudes and
practices (KAP) every six months to evaluate interventions and to further
tailor social mobilization and communications strategies.
India
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The number of
cases for 2009 is 650: 77 cases are type 1, 572 are type 3 and one is a type
1/type 3 co-infection. Last year at the same time, India had 524 cases: 65
type 1 and 459 type 3.
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The India
Expert Advisory Group (IEAG) reviewed the programme in November and
concluded that the country is firmly on the right path to finish polio
eradication. Wild poliovirus is now restricted to a very small geographical
area with only one surviving genetic lineage of type 1 polio. Research on
the recently developed bivalent OPV was reviewed and the IEAG recommended
its use in 2010, allowing continued prioritization of type 1 polio
elimination and simultaneous type 3 polio control. The Government of India
plans to use bOPV for the first time in Bihar in the January NID.
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Subnational
Immunization Days (SNIDs) were conducted on 8 November in the high-risk
areas of Bihar and Uttar Pradesh (UP), re-infected areas and areas known to
be destination points of large-scale population movements from these two
endemic states. Reports indicate that operations were improved in the
traditionally hard-to-reach Kosi River area of Bihar.
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Efforts
continue to close immunization gaps in young children and migrants - the
groups which are currently sustaining wild poliovirus transmission -
particularly in 107 high-risk blocks of western UP and central Bihar. Since
2003, over 80% of all type 1 polio cases have been reported from these 107
blocks (which represent approximately 2% of the country's geographic
blocks). Ensuring high OPV coverage during every SIA in these blocks is the
key to success.
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Eight VDPV
cases have been confirmed in 2009, two type 1 and six type 2. The date of
onset of paralysis of the most recent case was 14 October in UP. There are
plans to use trivalent OPV (tOPV) during the December SNID in selected areas
of West UP where type 2 VDPVs have been detected.
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The next SNIDs
will be conducted on 6 December, in key high-risk areas of Bihar, Uttar
Pradesh, re-infected areas, and areas known to be destination points of
large-scale population movements.
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Nationwide
polio campaigns (NIDs) are scheduled for 10 January and 7 February 2010. In
January, tOPV will be used all over the country except parts of Bihar.
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Four cricketers
from the Delhi and Uttar Pradesh local cricket teams came together to "Bowl
out Polio" on 26 November. Cricketers spoke in particular about the need to
wipe out polio in UP, home state to three of the players. Given the
significance of migrants in sustaining transmission, and the high migration
between Delhi and UP, players also spoke about the need for parents to
vaccinate their children, particularly when travelling.
Nigeria
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The number of
cases for 2009 is 384: 74 type 1 cases, 310 type 3. Last year at the same
time, Nigeria had 768 cases in total, 703 of which were type 1.
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No type 1 has
been recorded anywhere in the country for more than three months. The
operational improvements achieved this year during Supplementary
Immunization Plus Days (SIPDs) has resulted in a 50% decline in the overall
number of polio cases and a 90% decline in type 1 cases compared with 2008.
The intensity of transmission of all three serotypes (wild type 1, wild type
3 and circulating vaccine-derived poliovirus type 2 - cVDPV2) continues to
decline.
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During November
IPDs, sustained improvements in operations were again evident. In particular
in Kano, a traditional high-risk virus reservoir, religious, traditional and
local government area (LGA) leadership was visibly engaged, resulting in
strong community demand. The Emir of Kano officially launched these latest
activities by immunizing his grandson at a public Flag-Off ceremony.
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UNICEF
strengthened its technical presence in local level communication planning
and implementation at State and LGA levels through deployment of LGA
Consultants, STOP and Communication Consultants before the November IPDs.
The focus was also to build the capacity of partners to implement
communication activities in high-risk States.
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Journalists
against Polio (JAP) and the Forum of Muslim Women of Nigeria (FOMWON), both
with networks in the high-risk states in the north, are helping to ensure an
integrated approach to the implementation of communication activities,
including deployment of media monitors, capacity building, partnership with
the media and community meetings. Members of JAP and FOMWON have undergone
training and were deployed to the field for the November IPDs.
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In Sokoto and
Kebbi states, the November IPDs were postponed to early December.
Insecticide treated bed-nets are being distributed in select areas, as part
of the IPD strategy to offer additional health interventions to communities
during polio activities.
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Key messages
have been developed – based on social data from a KAP study – focusing on
immunization benefits, missed children and non-compliance. These have been
shared with state and local communication networks for their use in mass and
traditional media, and through interpersonal networks, such as key
traditional leaders, including the Sultan of Sokoto.
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The next IPDs
are nationwide and scheduled to start on 30 January and 27 February, 2010.
Pakistan
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Pakistan has
reported 81 cases in 2009 – 56 type 1 cases, 24 type 3 cases, and one type
1/type 3 co-infection – compared with 104 cases at the same time last year
(75 type 1 cases and 29 type 3).
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During the most
recent NIDs from 16-18 November, access was increased in key areas of North
West Frontier Province / Federally Administered Tribal Areas (NWFP/FATA).
The proportion of inaccessible populations dropped to its lowest level in
nearly two years (to 5% of the target population, compared to 18% in July).
However, greater Karachi (in Sindh) – a fully accessible area – demonstrated
operational gaps again. Full political ownership and accountability at the
implementation level (district and union council level) is urgently needed
to address the persistence of these operational gaps.
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Communications
reviews were held in NWFP/FATA and Sindh in November 2009. Review panel
members noted progress in the collection and use of data to identify the
local issues and to guide programme planning. Focus continues to be on the
development of local level plans based on data to address the local
challenges including access, awareness, mobilization of appropriate teams
and local level accountability.
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The partnership
between the polio eradication effort and Samaa TV was recognized at the 7th
Annual Asian Forum for Corporate Social Responsibility in the area of health
initiatives. The polio 'control cell' consistently supports the promotion of
polio campaigns by identifying underperforming teams and resulting in the
immunization of more than 25,000 missed children during vaccination
campaigns. President Asif Ali Zardari personally wrote to appreciate this
initiative and the award, reiterating the importance of media partnerships
in eradicating polio.
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The next SNIDs
will take place from 14-16 December.
Afghanistan
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Afghanistan has
reported 29 cases in 2009, 15 type 1 and 14 type 3, compared with 31 cases
at the same time last year - 24 type 1 cases and seven type 3.
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Since mid-year,
Afghanistan is affected primarily by type 3 transmission, restricted to
eight high-risk districts in security-compromised areas of the Southern
Region (Hilmand and Kandahar). Efforts during the most recent NIDs on 15-17
November again focused on increasing access in these districts.
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Concerted
efforts this year to engage traditional and community leaders, as well as
NGOs contracted by the Government to deliver the basic packages of health,
have led to increased access, particularly in the second half of the year,
during some SIAs. However, access continues to fluctuate from round to round
- in July, the proportion of inaccessible children was reduced for the first
time to less than 5% in the Southern Region (down from 20% at the start of
the year), while during this most recent November activity, this figure rose
slightly to 8%. This fact underscores the extreme and dangerous challenges
polio staff continue to face in efforts to implement the polio eradication
strategies.
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Bivalent OPV
will be used in SIAs – for the first time ever –during the next SNIDs from
13-15 December in Afghanistan, if supply is sufficient. In November 2007,
the ACPE had recommended the GPEI explore the potential benefits of a
bivalent OPV. A clinical trial conducted this year in India confirmed that
it would be a useful new tool in the arsenal of polio eradication, and the
vaccine is positioned for large-scale use in the GPEI by mid-2010.
ACPE
recommendations for re-infected countries included the following:
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The independent
monitoring process for the African Region presented to the ACPE should be
implemented as rapidly as possible in all re-infected countries, with
monitoring results made available internationally within 15 days of each
immunization round.
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SIAs should be
carried out in 2010 and 2011 in the areas at persistent high risk of
importation in West Africa, Central Africa, and the Horn of Africa (i.e. the
'importation belt'), prioritizing currently infected areas and those with
the weakest routine immunization coverage.
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Countries at
particular risk of polio importations should consider steps to ensure the
immunization of travellers arriving to or from infected areas - prior to
arrival and also at the point of entry - especially when large gatherings of
travellers are expected (such as the African Cup of Nations and the World
Cup).
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All identified
countries at persistent high risk of importation should review or develop
plans for strengthening routine immunization coverage.
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Angola and Chad
have documented evidence of re-established polio transmission by virtue of
the persistence of wild poliovirus for more than 12 months following
importation, and Sudan and DR Congo are at risk of having re-established
transmission. All four of these countries require the same levels of
political ownership and commitment as endemic countries, and will require
the same intensive level of partnership support.
West Africa
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West Africa has
recorded a total of 144 cases in 2009 (Benin 21; Burkina Faso
14; Côte d'Ivoire 27; Guinea 36; Liberia 10; Mali
5; Mauritania 4; Niger 15; Sierra Leone 6; and, Togo
6). All are type 1 except in Niger, which has one type 1 case and 14 type 3
cases.
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Niger has not
reported a case since May: a positive offshoot of the improvements in
Nigeria.
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Confirmation of
a type 1 case from Benin in October underscores the risk of ongoing
circulation of polio in the region. Genetic sequencing of this case is
currently ongoing, to determine if it is a new importation, or is sustained
transmission of earlier cases in this region of west Africa (i.e. Benin and
Burkina Faso).
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Farther west in
the region, the second-wave of the outbreak continues. Recent cases in
Mauritania are linked to earlier cases from Côte d'Ivoire.
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West Africa is
part of a well-defined belt of high-risk countries which are subject to
numerous and repeated importations (the others being in central Africa and
the Horn of Africa). In addition to the high risk of importations, these
areas are at high risk of subsequent secondary spread of imported virus
(resulting in local outbreaks), due to a combination of factors including
weak routine immunization.
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Ghana conducted
an immunization activity from 12 November (tOPV), as did Sierra Leone from
20 November (mOPV1), Niger from 21 November (tOPV), and Liberia from 23
November (mOPV1).
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A synchronised
immunization response will be held from 4 December
in Burkina Faso, Cote d'Ivoire, Mali and Mauritania, using mOPV1. Guinea
will hold an activity on 11 December and Mauritania again on 18 December,
while activities in Benin and Senegal are to be confirmed.
Horn of Africa
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No cases have
been reported across the Horn of Africa since July. The region has reported
71 cases in 2009 (Kenya: 18; Sudan: 45; and, Uganda:
8). Uganda has not recorded a case since 10 May, Sudan's last case had onset
of paralysis on 27 June and Kenya 30 July.
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All cases
across the Horn have been followed by at least two rounds of SIAs.
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Although no new
cases in the region have been reported since July, sub-national surveillance
gaps persist, particularly in southern Sudan, and interruption of polio
transmission needs to be verified.
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Success depends
on rapidly improving operational quality of SIAs in southern Sudan.
Political engagement at every level must be secured, in particular at the
county and 'Payam' level. Additionally, community mobilization must be
strengthened, to raise awareness of the dangers of polio and build demand
for immunization. In southern Sudan, national and international focal points
are being deployed to support each state effectively.
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Countries
across the Horn of Africa continue to be considered at high risk until
transmission of polio can be confirmed to have been interrupted, in the face
of strong sub-national surveillance.
Angola, DR Congo,
Burundi
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Angola
has recorded 28 type-1 cases in 2009, the most recent of which had onset of
paralysis on 15 September.
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SNIDs were held
in November in Benguela, Cuanza Sul, Cuanza Norte, Bengo (13-15 November)
and Luanda (20-22 November); for the first time, independent monitoring data
has been analysed within 15 days. This analysis (complete for the provinces
that went first), showed that on average, 16% of children monitored were not
vaccinated, as verified by finger-marking, with Benguela having as many as
34% not vaccinated in street surveys. Previously, significant operational
gaps - particularly in Luanda and Benguela - have marred the quality of
outbreak response. As a result, the outbreak has persisted for more than 12
months.
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In DR Congo,
no new cases have been recorded since 24 June. Though DR Congo has not
reported type 1 polio since late 2008, it is suspected of having
re-established transmission (with substantial periods of undetected virus)
and has documented spread to its neighbour Burundi, which has
recorded two cases this year.
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SIAs were held
on 17 November in Burundi, Rwanda and the province of South Kivu in DR
Congo, and on 26 November in North Kivu
Chad, CAR,
Cameroon
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Chad has
reported 48 cases in 2009 - all type 3. Central African Republic (CAR) has
reported 14 type 3 cases, while the newly infected Cameroon has reported
three type 3 cases, its first cases since 2006.
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In CAR, OPV was
delivered during Child Health Days held 20-24 November, focusing on the
polio-affected province of RS3. SIAs using tOPV are planned for 4 December
in Cameroon, as are NIDs in Chad.
_________________________________________________________________________________________________
Polio eradication will only succeed if the necessary funds are made
available, and with strong political commitment in polio-affected countries.
More than 10 million children will be paralysed in the next 40 years if the
world fails to capitalize on its >US$8 billion global investment in eradication.
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