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bullet Major Funding Announcement Boosts Polio Eradication Effort 
bullet Afghanistan honours polio workers killed in line of duty
bullet UNICEF Redesigns Polio Teams in Nigeria and India
bullet Polio goes to the Oscars
bullet Spearheading partners inducted into Polio Hall of Fame in Warm Springs 
bullet Africa: synchronized outbreak response
bullet Pakistan tackles polio — from police to politicians 

ITECHNICAL TIPS
bullet Global advisory body outlines challenges and solutions to ending polio transmission in remaining endemic countries
         Nigeria        
         Afghanistan     
         India
         Pakistan 
DATA
bullet Nigeria: improvement in zero dose children in highest-risk areas
bullet Response to outbreak in Africa
 
RESOURCE MOBILIZATION
bullet Financial Resource Requirements for 2009-2013 published
bullet Rotary puts spotlight on polio eradication
bullet UK boosts funds to eradicate polio in Pakistan
bullet Indian individuals rally to end polio now 
bullet Moving snapshot of Indian Immunization Day
bullet New Contributions/Projections received between August 2008 - March 2009, for the period 2009-2010
bullet Publications and resources on www.polioeradication.org 
bullet Events

 

Major Funding Announcement Boosts Polio Eradication Effort

Bill Gates immunizes a child during his visit to Nigeria in January and, inset, witnessing a National Immunization Day in India. The cap he is wearing was later signed and sold at auction for $17 600.

The Bill and Melinda Gates Foundation, Rotary International, and the British and German governments have this year committed more than US$ 630 million in funding to stop polio. On 21 January, the Gates Foundation announced it was awarding a US$ 255 million challenge grant to Rotary, which Rotary will match with US$ 100 million from its members over the next three years. In addition, the United Kingdom and Germany are committing US$ 150 million and US$ 130 million, respectively, over the next five years*.

“Rotarians, government leaders, and health professionals have made a phenomenal commitment so polio afflicts only a small number of the world’s children,” said Bill Gates, co-chair of the Gates Foundation. “Rotary in particular has inspired my own personal commitment to get deeply involved in achieving eradication.”

Mr Gates reaffirmed that his Foundation was prepared to go the distance to see eradication achieved. “Eradicating a disease is hard, slow, painstaking work,” he told a Rotary convention in San Diego in January. But failure was “no alternative at all - we don’t let children die because it is fatiguing to save them”.

The donors have earmarked these funds to be allocated to

 


support supplemental immunization activities, including the purchase of oral polio vaccine, in polio-endemic countries and countries with imported cases; research into new vaccines and ways to ensure they are available to vulnerable children; and surveillance to detect polio cases and respond swiftly to outbreaks in neighbouring countries.

These contributions signal a clear vote of confidence in the intensified polio eradication effort launched in 2007. This intensified effort has proven, according to the Advisory Committee on Poliomyelitis Eradication (ACPE) and the Strategic Advisory Group of Experts on Immunization (SAGE), that the remaining technical, financial, and operational challenges to polio eradication, even in

 

 

 

 

 

 

 

 

 

 

key areas of each endemic country, can be overcome (see Page 4-5 for more information).

However, recognizing the unique challenges in the remaining polio-endemic countries and re-infected regions, the WHO Executive Board (EB) has requested a country-specific evaluation to guide polio eradication’s next vital steps.

*For the critical two-year period of 2009-2010, a global polio funding gap of US$340 million remains, of which $55 million is needed in 2009.

Afghanistan honours polio workers killed in
line of duty

Afghanistan President Hamid Karzai has held a special ceremony to honour the lives of two doctors and their driver killed on WHO duty when attacked by a vehicle-borne suicide bomber. On 12 January, Mr Karzai made a presentation to the families of Dr Mamoon Taher Taheri, Dr Shamsul Haq M.H. Kakar and their driver Azizullah Almas, who were killed in Kandahar Province on 14 September while preparing logistics for a regional polio vaccination campaign to be carried out on UN Peace Day.

Dr. Hussein A. Gezairy, EMRO Regional Director, attended the event and gave his deepest condolences to the men’s families.

“It is tragic beyond words that their dedication to a humanitarian mission should have ended in the loss of their lives,” Dr Gezairy said. “While we will never forget

those whom we have lost, we must rise above this challenge and do everything possible to reach the target. This will be the best acknowledgement to all those lost during the polio eradication efforts.”

The UN Secretary-General and WHO Director General also both strongly condemned the killings. Although the suicide bombing

threatened to derail the polio immunization campaigns, the national team leading the polio eradication effort in Afghanistan felt that completing the planned immunization days was the best way to remember their colleagues. The death of these men is a poignant reminder of the extraordinary sacrifices that continue to be made in the name of eradicating polio.

UNICEF Redesigns Polio Teams in Nigeria and
India

UNICEF India Country Representative Karin Hulshof, left, and Nigeria Representative Dr Suomi Sakai.

UNICEF Representatives in Nigeria and India have reorganized their polio teams to place a greater emphasis on stopping transmission soon, placing all of the core polio program functions (program communication, media and advocacy, vaccine supply and logistics) in one unit reporting to a senior manager responsible only for polio eradication.

Some key appointments are overseeing the changes in both countries. In India, Karin Hulshof (previously director of UNICEF’s Programme Funding Office) has been named India Representative, with Lieven Desomer - one of UNICEF’s most experienced immunization experts, having led UNICEF’s effort to support EPI programs in Nigeria, Democratic Republic of Congo and Somalia - appointed to lead the polio program.

In Nigeria, Dr Suomi Sakai has taken over as Country Representative after previously serving as Representative in Cambodia and Nepal, and UNICEF’s Chief of Immunization.

Dr Sakai said UNICEF Nigeria was currently recruiting for the new “focused and streamlined” structure, with staff hopefully in place in the first half of this year. “In this team we have not only the dedicated polio specialists but also the media and the communications staff focused on engaging the communities. We’re bringing all of that together so our staff can be more dedicated to focusing on polio, with obvious links to the routine immunization system,” Dr Sakai said. “The other element is that in each of the zone offices in the field we have people who are polio-focused. This is a job that needs to get done.”

 

 

 

 

While encouraged by displays of re-engagement in polio eradication by high-ranking government officials, Dr Sakai said there was no room for complacency. “There is re-engagement, yes, but it’s something that needs to continue,” she said, adding that much more needed to be done at a local level. “We need to provide the local-level leadership with the tools and the right questions to monitor the polio program and ensure that they’re getting results.”

Polio goes to the Oscars

A film taking a first-person look at the massive challenge of clearing the final hurdle in polio eradication was nominated for an Academy Award in the best documentary short subject category. The Final Inch, a 38-minute film commissioned by the philanthropic division of Google, chronicles the challenges health organizations and governments face during the final stages of polio eradication.

The film follows health workers as they go door to door immunizing Indian children during National Immunization Days, clearly illustrating the final challenges in the remaining few polio-endemic areas. Director and producer Irene Taylor Brodsky juxtaposes their experience with the memories of polio survivors in the United States, placing the challenge of eradication

against the context of the reward for generations to come. The Final Inch will air on HBO in the United States in early April.

Spearheading partners inducted into
Polio Hall of Fame in Warm Springs

All those who had a role in the 50th Anniversary Induction Ceremony are pictured at the newly upgraded Polio Hall of Fame Monument moments after its unveiling, including RWSIR Executive Director Greg Schmieg, State Representative and RWSDF Trustee Carl Von Epps, Georgia Labor Commissioner Michael Thurmond, FDR grandson H. Delano Roosevelt, Jonas Salk’s eldest son Peter Salk, U.S. Congressman Ike Skelton, Rotary International PolioPlus Director Carol Pandak, World Health Organization External Relations Officer Werner Obemeyer, CDC Immunization Director Anne Schuchat and UNICEF Senior Health Advisor Ahmed Magan.

Africa: synchronized outbreak response

Historic seven-country cross-border synchronized vaccination campaign across
West Africa immunizes 55 million children on one weekend.

Wild virus type 1 Wild virus type 3 Spread of virus
Rolling 6-months map. Data in WHO/HQ as of April 2009. Immunization response.

In the second half of 2008, a polio outbreak in northern Nigeria spread to west Africa, with 55 polio cases linked to northern Nigeria confirmed in Benin, Burkina Faso, Chad, Côte d’Ivoire, Ghana, Mali, Niger and Togo (as of 18 March, 2009).

As part of the response, a seven-country synchronized cross-border immunization campaign was held across west Africa from 27 February-2 March (Ghana conducted its first-round immunization day on 12 February), with a second round from 27-30 March.

More than 28 million children from Benin, Burkina Faso, Cote d’Ivoire, Mali, Niger and Togo were immunized by almost 95,000 immunizers carrying 33 million oral polio vaccine doses. A further 25 million children were immunized on these days with mOPV1 in 15 states in Nigeria. High-quality acute flaccid paralysis (AFP) surveillance is now underway to detect any further cases and verify when transmission has been halted.

An outbreak of wild poliovirus

type 1 - previously restricted to southern Sudan and western Ethiopia - has spread to northern Kenya, northern Uganda and northern Sudan (Khartoum and Port Sudan). The report of a case in Port Sudan is worrying, given it was from this port city that an outbreak spread to Saudi Arabia, Indonesia, Somalia and Yemen in 2004-06, resulting in 1,200 cases and requiring more than US$ 150 million in international emergency outbreak response costs.


Detection of polio sparked rapid outbreak response activities in the re-infected countries. Genetic sequencing data suggests that the importations into these countries have been rapidly detected, improving the prospects for interrupting transmission in the near term.

In northern Sudan, a large-scale supplementary immunization activity (SIA) began on 15 February and continued on 23 March, with more planned for late April.

In southern Sudan, rapid-fire

A civilian volunteer trained by WHO and the Sudanese Ministry of Health administers polio vaccine to a long line of schoolchildren in Sudan in February.

SIAs were held on 13 January, 23 February, 23 March and late April in the hope of delivering the optimum number of doses before the onset of the rainy season in May, when access becomes difficult. The President of the Government of Southern Sudan, His Excellency General Salva Kiir, has declared the outbreak a national emergency and pledged to do all he can to support the emergency response.

Pakistan tackles polio — from police to
politicians

A Pakistani policewoman joins the battle to tackle polio at an immunization booth at a motorway toll station.

If your car is stopped by police in Pakistan during an immunization activity, you’re just as likely to be asked if the children in the car have been immunized against polio as you are to have your driver’s licence checked. Since late last year, police, together with district health teams, have been manning vaccination booths at border crossings, transit points, road stops and bus stops - including 58 toll booths - in targeted regions of Pakistan.

Meanwhile, on busy train station platforms, Railways Health staff are setting up vaccination booths and immunizing children as they get on and off trains. These are crucial examples of how Pakistan is tackling one of its greatest challenges in eradicating polio - ensuring that children who move into and out of high-risk poliovirus

 

 

 

 

areas, including across the border into Afghanistan, are immunized.

This civil support and co-operation is being driven from the top down: on 26 February, the Prime Minister of Pakistan Syed Yusuf Raza Gilani, chaired a meeting at the Ministry of Health, Islamabad,

 

 

 

 

and approved an Action Plan for polio eradication in Pakistan. This plan focuses mainly on securing the active involvement of other sectors beyond the health sector to support polio eradication efforts, to ensure a truly national campaign.

Technical Tips

Global advisory body outlines challenges and solutions to ending polio transmission in remaining endemic countries

In February, 2007, the Global Polio Eradication Initiative launched the Intensified Eradication Effort.
In November 2008, the Advisory Committee on Poliomyelitis Eradication (ACPE) declared the
Intensified Eradication Effort had proven that although the remaining endemic countries - Nigeria,
India, Pakistan and Afghanistan - posed unique challenges, polio eradication could be achieved.

Nigeria

The Governor of Kano, Malam Ibrahim Shekerau, demonstrates his commitment to polio eradication by immunizing his own child to launch an Immunization day in the State.

“Nigeria will continue to pose a high risk to international health until the new, top political commitment is translated into field level improvements in campaign quality.” - ACPE CONCLUSION

Primary challenge:

  • If 90% of Nigeria’s children under five receive three doses of vaccine, the country will halt polio transmission. Despite increased community demand for polio immunization, operational issues are affecting the quality of vaccination campaigns, particularly in the highest-risk northern states, where more than 60% of children are under-immunized. The primary challenge is to overcome the sub-optimal delivery of OPV during SIAs.
  • Nigeria benefits from a renewed high-level political engagement. In February 2009, under the leadership of HE President Umaru

Yar’Adua, the governors of the 36 states of Nigeria collectively signed the ‘Abuja Commitments to Polio Eradication in Nigeria, publicly committing themselves to provide the necessary active leadership urgently needed for polio eradication.

Strategic approaches:

  • Systematically translating new high-level engagement into engagement at State and Local Government Area (LGA - district) level, to urgently improve operational quality of vaccination campaigns. Progress has been seen in areas where state governors and LGA Chairpersons are fully engaged.
  • Putting in place International monitoring systems – based on experience in other countries – to evaluate LGA-level engagement and accountability to ensure the full implementation of the ‘Abuja Commitments’.

 


 

 

 

 

 

  • In long-standing areas of low coverage which have international implications, notably Kano, scaling-up international technical support.
  • Scaling-up activities to further enhance community engagement, including through the systematic and regular assessment of community perceptions and tailoring of social mobilization activities as necessary.

Afghanistan

Afghanistan has an eradication program which, with modest improvements in access in security-compromised areas and campaign oversight and quality in accessible areas, should interrupt poliovirus transmission.” - ACPE CONCLUSION

Primary challenge:

  • Polio transmission in Afghanistan is primarily restricted to the country’s Southern Region, where access to all populations during SIAs is hampered by insecurity.

Strategic approaches:

  • Implementing quarterly programme reviews to quantify and prioritize problems and their implications based on the evolving security situation, population size and movements, and number of missed children during each SIA.
  • Applying area-specific tactics, based on experience in other conflict-affected areas and the quarterly reviews.
  • Enhancing negotiations with community leaders, irrespective of affiliation, to allow increased and safe passage to all populations by vaccination teams.
  • In between large-scale NIDs and subnational immunization days (SNIDs), during any window of opportunity as they arise, delivering an extra dose of vaccine to communities (Short Interval Additional Dose strategy – SIAD).

India

India has a very high-performing eradication program which, if current efforts are sustained and contingency plans rapidly implemented to enhance program efficacy, will interrupt poliovirus transmission.” - ACPE CONCLUSION

Primary challenge:

  • India benefits from a highly performing eradication program, with more than 95% coverage during vaccination campaigns. During National Immunization Days (NIDs), more than 172 million children are immunized in just six days. However, due to several contributing factors -- high population levels living in close density (in Uttar Pradesh alone, 500,000 children are born each month); frequent population movements; inadequate sanitation infrastructure, and suboptimal routine health services -- efficacy of oral polio vaccine (OPV) is

sub-optimal in the remaining infected areas of the country, notably in the western part of Uttar Pradesh.

  • Key to success is maximising the impact of each immunization, and sustaining the high-quality SIA operations.

Strategic approaches:

  • Implementing large-scale vaccination campaigns every four to six weeks in Uttar Pradesh and Bihar, with monovalent OPV type 1 (mOPV1).
  • Implementing cross-cutting new initiatives, including the use of inactivated polio vaccine (IPV), higher titre mOPV1, and developing bivalent OPV as a supplement to current immunization campaigns with mOPV1 in highest-risk districts of northern India. Strategically optimizing the mix of vaccines to prioritize interruption of type 1 polio transmission, while maintaining immunity to type 3

    polio and protecting polio-free areas.

  • In response to any further detected type 1 cases, immediately implementing large-scale mOPV1 mop-ups at the district-level.
  • Regularly conducting international review of SIA operations (and monitoringing for implementation of recommendations). During SIAs, immediately re-covering all areas achieving <90% coverage.
  • Developing and systematically implementing specific strategies to reach hard-to-reach populations, including migrant populations and populations living in remote areas.

Pakistan

Pakistan has an eradication program which is sound, but which, because of very efficient virus transmission, gaps in campaign quality, and a deterioration in security in a key transmission zone, requires further improvements in campaign quality and continued innovation to interrupt poliovirus transmission.” - ACPE CONCLUSION

Primary challenges:

  • Hampered access to populations in security-compromised areas, such as North-West Frontier Province/Federally Administered Tribal Areas (FATA), coupled with large-scale population movements, including with neighbouring Afghanistan, make reaching immunization targets difficult.
  • At the same time, in some accessible areas of the country (eg Sindh), operational challenges continue to hamper vaccination efforts.
  • Due to this, as well as frequent population movements, a

cross-sectoral approach is needed to interrupt the remaining chains of polio transmission. Key is full provincial- and district-level engagement, which will ensure that supervisor and implementing staff are accountable to improving the quality of SIA operations.

  • Pakistan benefits from strong high-level political engagement. In February 2009, Prime Minister of Pakistan Syed Yousaf Raza Gillani launched a ‘Polio Action Plan’, with the immediate aim of assuring inter-sectoral support for polio eradication and fostering provincial- and district-level accountability.

Strategic approaches:

  • Putting in place international monitoring systems to monitor the engagement of provincial and district leaderships.
  • Developing provincial-level operational plans to target eradication strategies. Independently monitoring SIA performance through finger-marking, and immediately re-covering

    all areas achieving <90% coverage.

  • In areas where programmatic and epidemiological data are discordant, implementing seroprevalence surveys to verify programme performance and vaccine efficacy.
  • To maintain population immunity and minimise the risk to polio-free areas, strategically optimising bivalent OPV use, alongside mOPVs and trivalent OPV.
  • To increase access to populations in security-compromised areas, implementing quarterly risk assessments and assess their implications, and applying area-specific tactics, based on experience in other conflict-affected areas.
  • Enhancing negotiations with community leaders, irrespective of affiliation, and systematically rolling out the SIAD strategy to deliver an extra dose of vaccine to communities in between large-scale NIDs and SNIDs, as any window of opportunity arises.

Data

Nigeria: improvement in zero dose children
in highest-risk areas

Zero Dose 1-2 Doses 3+ Doses
Source of data: OPV status of non-polio AFP cases.

Response to outbreak in Africa
(date of activity plus target population)

Resource Mobilization

Financial Resource Requirements
for 2009-2013 published

A draft Financial Resource Requirements (FRR) document outlining a five-year budget through 2013 was made available in January 2009. This preliminary FRR, to be refined in May, summarizes the funding needed to successfully interrupt wild poliovirus transmission globally and prepare for the post-eradication era. The FRR was developed in conjunction with the framework for a new global polio eradication initiative strategic plan for the same period (2009-2013), which has been endorsed by the Advisory Committee for Polio Eradication (ACPE). The document is available at www.polioeradication.org.

Rotary puts spotlight on polio eradication

From Sydney’s Opera House to Rome’s Coliseum, from Cape Town’s Table Mountain to New York’s High Falls, Rotary’s commitment to “End Polio Now” has been lighting up the night sky. Throughout the third week of February, floodlit messages across some of the world’s most iconic landmarks called on the millions that saw them to join the remarkable 20-year campaign to rid the world of polio. “By illuminating these historic landmarks with our pledge to end polio, Rotary clubs are announcing to the world that we will not stop until the goal is achieved,” says Jonathan Majiyagbe, the Rotary Foundation’s trustee chair.

“We hope people everywhere will see these words, either in person or through the media, and join

with us and our partners in this historic effort to rid the world of polio once and for all.”

UK boosts funds to eradicate polio in Pakistan

On October 21, the United Kingdom’s Department for International Development (DFID) announced that it will provide an additional £7.5 million (US$ 13.5 million) through WHO to help eliminate polio in Pakistan.

The new funds will be used to

support supplementary immunization activities.


In announcing the additional funding, the Minister for International Development, Mike Foster, paid tribute to the Pakistan Government’s efforts. “We are proud to be

a partner in Pakistan’s quest to fight polio, and we commend the government of Pakistan for its work to safeguard all children from this disease.”

The UK has contributed US$ 894 million since 1988 to eradicate polio.

Indian individuals rally to end polio now

Rajashree Birla welcomes Bill Gates to the meeting with Rotarian business leaders in New Delhi. At left is Past RI President Rajendra K. Saboo.

Three Indian individuals made a November dinner meeting between Bill Gates and Rotary business leaders in India a night to remember when between them, they donated US$ 2.75 million.

Rajashree Birla, who had already contributed US$ 1 million to Rotary’s challenge in early 2008, committed a further US$ 1 million, Rotary member Harshad R. Mehta, who has already committed US$ 2 million to the challenge, committed an additional US$ 1.5 million, and Rotary member Rajnikant D. Shroff Gujarat committed US$ 250,000.


 

 

 




“India’s leaders have made significant investments to protect its 172 million children from polio,” Bill Gates said at the meeting.

 

 

 

 

 

 

 

 

 

 

“The commitment from everyone involved is impressive, especially Rotary International, that has launched their worldwide program.”

Moving snapshot of Indian Immunization Day

Photojournalist Richard Wainwright joined Rotary on a National Immunization Day in Saharanpur, northern Uttar Pradesh, on 1 February. To see his excellent slideshow of what it takes to immunize each child in India under five against polio, go to www.richwainwright.com.

New Contributions/Projections received
between August 2008 - March 2009, for the period
2009-2010 (in $US millions)

As of 17 March 2009
* Rotary International will contribute US$255 million to the GPEI for the period 2008-2013.
** The UK will contribute £100 million in global funding to the GPEI for the period 2008-2012, in addition to specified funding for Pakistan (‘08-’09).
*** The 2008 figure represents the remaining balance of the full Congressional allocation + an additional $400,000 from USAID.

Publications and resources on www.polioeradication.org

  • Polio Pipeline, Issue 02, Autumn 2008
  • Polio Pipeline, Issue 03, Winter 2009
  • Financial Resource Requirements, 2009-2013 (as of March, 2009)
  • Abuja Commitments to Polio Eradication
  • Framework for the new GPEI Strategic Plan 2009-2013
  • Progress Report from 124th Session of Executive Board to the World Health Assembly (Jan 2009)
  • Final Report of the Advisory Committee on Polio Eradication (ACPE) (Dec 2008)
  • Strategic Advisory Group of Experts on Immunization (SAGE) meeting (Nov 2008)

Events

  • April 7-9: SAGE meeting, Geneva, Switzerland
  • May 12-14, EMRO Regional Certification Commission meeting, Cairo, Egypt
  • May 13-22, STOP 31 Field Training, Atlanta, USA
  • May 18-27: 62nd World Health Assembly, Geneva, Switzerland
  • June 1-3: Polio Research Committee meeting, Geneva, Switzerland
  • June 3-4: SAGE Intravenous Polio Vaccine Working Group meeting, Geneva, Switzerland
  • June 21-24: Rotary Convention, Birmingham, UK
  • June 23-25: 15th Informal Consultation of LAB Network, Geneva, Switzerland

The Global Eradication of Polio